The Effects of Titanium Tetrafluoride and Sodium Fluoride on Calcium Loss from Bleached Enamel

1 2 Background: Application of topical fluoride agents has been shown to be the most effective method in 3 treating demineralized enamel after in-office bleaching treatments. Thus, this study aimed to examine the 4 effects of two different post-bleaching fluoridation agents (1.5% titanium tetrafluoride and 2.1% sodium 5 fluoride) on the calcium loss of enamel after an acidic challenge. 6 Methods: Ten maxillary premolars were sectioned into four pieces each, to be assigned to one control and 7 three treatment groups. After bleaching the specimens in three test groups with 38% hydrogen peroxide, two 8 out of the three test groups were treated with fluoride agents with different concentrations; 1.5% titanium 9 tetrafluoride and 2.1% sodium fluoride. Then all specimens were subjected to a demineralization process 10 four times for four days to be tested after 16 days for their calcium loss with atomic absorption 11 spectrophotometer. The calcium released to buffer after the 4th, 8th, 12th and 16th days were compared with 12 Repeated Measures ANOVA and Bonferroni as Post Hoc Tests. 13 Results: The calcium released from the fluoride-applied groups was lower when compared to the 38% 14 hydrogen peroxide and control group. At the end of the 16 day the amount of calcium released from 15 titanium tetrafluoride-treated samples were less than sodium fluoride-treated samples. 16 Conclusions: Fluoride application decreased the amount of calcium released after bleaching with 38% 17 hydrogen peroxide. Titanium tetrafluoride treated samples released less calcium than sodium fluoride 18 treated samples 19 Clinical Relevance: The application of topical 1.5% titanium tetrafluoride and 2.1% sodium fluoride agents 20 might be beneficial after the bleaching process with 38% hydrogen peroxide. 21